Cecilia Chao

Adjunct Lecturer

Dr Cecilia Chao is an Associate Lecturer at the School of Optometry and Vision Science, UNSW Sydney and is currently conducting her post-doctoral work at Tufts Medical Center in Boston USA. She was previously trained as a translational post-doctoral fellow in the State University of New York, College of Optometry with Associate Professor Kathryn Richdale.

Dr Chao's current research in Professor Pedram Hamrah’s lab in Boston focuses on corneal and lacrimal gland conventional dendritic cells morphology and kinetic properties in vivo after environmental dry eye exposure using multi-photon microscopy. She is also investigating the selective blockade of chemokine receptors and/or integrins from HSV-1 primed CD4 T cells on their homing to the cornea, which will lead to the development of the treatment for HSV-1 keratitis. Her other research expertise includes contact lens induced sub-clinical inflammatory responses on the ocular surface, post-LASIK induced neuropathic dry eye, corneal subbasal nerve regeneration and its association with corneal dendritic cells and tear neuropeptides.  

Dr Chao currently co-supervises research projects of PhD students in the fields of corneal antigen-presenting cell using in vivo confocal microscopy and tear cytokines during contact lens wear at UNSW in order to enhance the student experience and maximise learning whilst conducting their research. 

Publications

Conference Abstracts
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Chao C; Ortiz G; Jamali A; Hamrah P, 2019, 'Chemokine receptors CXCR3 and CCR4 mediate corneal CD4(+) T cell homing during herpes simplex virus-1 keratitis', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Vancouver, CANADA, Vol. 60, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Vancouver, CANADA, 28 April 2019 - 02 May 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488800702389&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Stapleton F; Chao C; Jalbert I; Mandathara P; Kolanu S; Willcox M; Markoulli M; You JJ; Kim J; Lum E; Golebiowski B, 2016, 'Relationships between central corneal nerve parameters and tear neuropeptides', in Invest Ophthalmol Vis Sci, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Seattle, WA, Vol. 57, pp. E - abstract 2796, presented at ARVO Annual Meeting, Seattle, WA, 01 May 2016 - 05 May 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000394210605041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2016
Chao C; Golebiowski B; Zhou X; Chen S; Zhou S; Stapleton F, 2015, 'Tear CGRP and SP and corneal reinnervation after LASIK', in Invest Ophthalmol Vis Sci, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Denver, CO, Vol. 56, presented at ARVO Annual Meeting, Denver, CO, 03 May 2015 - 07 May 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000362882202061&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2015
Stapleton F; Badarudin N; You JJ; Hampel U; Eden J; Raisin L; Williams J; Chao C; Golebiowski B, 2015, 'Determinants of ocular symptoms in postmenopaual women with dry eye', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Denver, CO, Vol. 56, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Denver, CO, 03 May 2015 - 07 May 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000362891103255&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Conference Papers
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Mobeen R; Chao C; Stapleton F; Madigan M; Golebiowski B, 2019, 'Corneal epithelial dendritic cell density in a healthy population and its relationship with age and sex: A Meta-Analysis of in vivo confocal microscope data', in Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, Vancouver, presented at ARVO, Vancouver, 28 April 2019 - 02 May 2019
2019
Tajbakhsh Z; Chao C; Mobeen R; Golebiowski B; Stapleton F; Jalbert I, 2019, 'Development of a novel corneal epithelial dendritic cell morphology grading scale', in Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, Vancounver, Canada, presented at ARVO, Vancounver, Canada, 28 April 2019 - 02 May 2019
2019
Richdale K; Chao C; Gokhale M; Duong K; Madigan M; Jalbert I; Golebiowski B; Willcox M, 2017, 'Sex, Tears and Contact Lenses', in Sex, Tears and Contact Lenses, 8th International Conference on the Tear Film & Ocular Surface: Basic Science and Clinical Relevance, Montpellier, France, presented at 8th International Conference on the Tear Film & Ocular Surface: Basic Science and Clinical Relevance, Montpellier, France, 07 September 2016 - 10 September 2016
2017
Chao C; Golebiowski B; Stapleton F; Richdale K, 2017, 'Conjunctival cell morphology and goblet cell density in soft contact lens wearers', in Conjunctival cell morphology and goblet cell density in soft contact lens wearers, American Academy of Optometry Annual Meeting, Anaheim, CA, USA, pp. E-Abstract: 165084 - E-Abstract: 165084, presented at American Academy of Optometry Annual Meeting, Anaheim, CA, USA, 09 November 2016 - 12 November 2016
2017
Chao C; Richdale K; Willcox MDP, 2017, 'Inflammatory mediator uptake and release in contact lens materials - a preliminary experimental report', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Baltimore, MD, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Baltimore, MD, 07 May 2017 - 11 May 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432176300061&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2017
Golebiowski B; Bui K; Lam W; Chao C; Richdale K; Stapleton F, 2016, 'The effect of age and contact lens wear on corneal Langerhans cells', in Invest Ophthalmol Vis Sci, ARVO Annual Meeting, Seattle, WA, pp. E - abstract 4734, presented at ARVO Annual Meeting, Seattle, WA, 01 May 2016 - 05 May 2016
2016
Chao C; Golebiowski B; Zhou X; Chen S; Zhou S; Stapleton F, 2015, 'Tear CGRP and SP and corneal reinnervation after LASIK', in Invest Ophthalmol Vis Sci, ARVO Annual Meeting, Denver, CO, pp. E - abstract 722, presented at ARVO Annual Meeting, Denver, CO, 03 May 2015 - 07 May 2015
2015
Stapleton F; Badarudin N; You JJ; Hampel U; Eden J; Raisin L; Williams J; Chao C; Golebiowski B, 2015, 'Determinants of ocular symptoms in postmenopausal women with dry eye.', in Invest Ophthalmol Vis Sci, ARVO Annual Meeting, Denver, CO, pp. E - abstract 4473, presented at ARVO Annual Meeting, Denver, CO, 03 May 2015 - 07 May 2015
2015
Conference Presentations
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Richdale K; Chao C; Gokhale M; Duong K; Madigan M; Jalbert I; Golebiowski B; Willcox M, 2016, 'Sex, Tears and Contact Lenses', presented at 8th International Conference on the Tear Film & Ocular Surface: Basic Science and Clinical Relevance, Montpellier, France, 07 September 2016 - 10 September 2016
2016
Journal articles
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Chao C; Richdale K; Willcox M, 2019, 'Absorption and Extraction of Inflammatory Mediators From Contact Lens Materials', Eye & contact lens, vol. 45, pp. 340 - 345, http://dx.doi.org/10.1097/ICL.0000000000000576
2019
Chao C; Richdale K; Willcox M, 2019, 'Absorption and Extraction of Inflammatory Mediators From Contact Lens Materials.', Eye Contact Lens, vol. 45, pp. 340 - 345, http://dx.doi.org/10.1097/ICL.0000000000000576
2019
Mobeen R; Stapleton F; Chao C; Madigan M; Briggs N; Golebiowski B, 2019, 'Corneal epithelial dendritic cell density in the healthy human cornea: A meta-analysis of in-vivo confocal microscope data', Ocular Surface, http://dx.doi.org/10.1016/j.jtos.2019.07.001
2019
Golebiowski B; Chao C; Bui KA; Lam W; Richdale K; Stapleton F, 2019, 'Effect of age and contact lens wear on corneal epithelial dendritic cell distribution, density, and morphology', Contact Lens and Anterior Eye, vol. in press, http://dx.doi.org/10.1016/j.clae.2019.05.002
2019
Stapleton F; Chao C; Golebiowski B, 2019, 'Topical Review: Effects of Contact Lens Wear on Corneal, Conjunctival, and Lid Margin Sensitivity', Optometry and Vision Science, vol. 96, pp. 790 - 801, http://dx.doi.org/10.1097/opx.0000000000001429
2019
Chao C; Akileswaran L; Bailey JNC; Willcox M; Van Gelder R; Lakkis C; Stapleton F; Richdale K, 2018, 'Potential role of ocular microbiome, host genotype, tear cytokines, and environmental factors in corneal infiltrative events in contact lens wearers', Investigative Ophthalmology and Visual Science, vol. 59, pp. 5752 - 5761, http://dx.doi.org/10.1167/iovs.18-24845
2018
Ambaw YA; Chao C; Ji S; Raida M; Torta F; Wenk MR; Tong L, 2018, 'Tear eicosanoids in healthy people and ocular surface disease', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-29568-3
2018
Chao C; Tong L, 2018, 'Tear lactoferrin and features of ocular allergy in different severities of meibomian gland dysfunction', Optometry and Vision Science, vol. 95, pp. 930 - 936, http://dx.doi.org/10.1097/OPX.0000000000001285
2018
Golebiowski B; Chao C; Stapleton F; Jalbert I, 2017, 'Corneal Nerve Morphology, Sensitivity and Tear Neuropeptides in CL Wear', Optometry and Vision Science, vol. 94, pp. 534 - 542, http://dx.doi.org/10.1097/OPX.0000000000001063
2017
Chao C; Richdale K; Jalbert I; Doung K; Gokhale M, 2017, 'Non-invasive objective and contemporary methods for measuring ocular surface inflammation in soft contact lens wearers – A review', Contact Lens and Anterior Eye, vol. 40, pp. 273 - 282, http://dx.doi.org/10.1016/j.clae.2017.05.008
2017
Chao C; Stapleton F; Golebiowski B; Willcox M; Richdale K, 2017, 'Pre-inflammatory Signs in Established Reusable and Disposable Contact Lens Wearers', Optometry and Vision Science, vol. 94, pp. 1003 - 1008, http://dx.doi.org/10.1097/OPX.0000000000001129
2017
Chao C; Golebiowski B; Stapleton F; Richdale K, 2016, 'Changes in tear cytokine concentrations following discontinuation of soft contact lenses-a pilot study', Eye and Contact Lens, vol. 42, pp. 1 - 7, http://dx.doi.org/10.1097/ICL.0000000000000182
2016
Golebiowski B; Chao C; Stapleton F; Richdale K, 2015, 'Changes in tear cytokine concentrations following discontinuation of soft contact lenses - a pilot study', Eye & Contact Lens: Science & Clinical Practice, vol. 42, pp. 1 - 7, http://dx.doi.org/10.1097/ICL.0000000000000182
2015
Chao, C, Stapleton, F, Badarudin, N, Golebiowski, B. , 2014, 'Ocular Surface Sensitivity Repeatability with Cochet-Bonnet Esthesiometer', Optometry and Vision Science, vol. 92, pp. 183 - 189, http://dx.doi.org/10.1097/OPX.0000000000000472
2014
Chao C; Golebiowski B; Cui Y; Stapleton F, 2014, 'Development of a Chinese version of the ocular comfort index', Investigative Ophthalmology and Visual Science, vol. 55, pp. 3562 - 3571, http://dx.doi.org/10.1167/iovs.14-14276
2014
Chao C; Golebiowski B; Stapleton F, 2014, 'The role of corneal innervation in lasik-induced neuropathic dry eye', Ocular Surface, vol. 12, pp. 32 - 45, http://dx.doi.org/10.1016/j.jtos.2013.09.001
2014