Carol Morris

Adjunct Associate Professor

Carol obtained her PhD in Biochemistry from the University of Sydney in 1971, and after a 5 year Post-Doctoral period in Microbiology she built a research and teaching career in the Medical Sciences.  She has always been interested in the applied aspects of her scientific research, interspersing periods in Academia with some in Industry, including a small Australian start-up company in Diagnostics.  In 1992, through a chance meeting with Brien Holden, she began to focus her attention on the biology of the anterior eye, and contact lenses.  Carol has worked in R & D for two contact lens companies in the US, Cibavision (6 years) and more recently CooperVision (7 years), where she has contributed to areas of contact lens comfort, biocompatibility of materials and additives and the minimization of adverse events.   She is best known for her scientific contributions on the composition of tears; in health, in various physiological states and in disease.  During her career Carol has published over 40 research papers, two book chapters, successfully supervised 18 post-graduate students, given a number of invited presentations at Research Symposia, and is a named inventor on several issued patents and patent applications.  She is currently on the Editorial Board of Nutrition Research, and a frequent reviewer for IOVS, Eye and Contact Lens and Optometry and Vision Science.

Publications

Conference Papers
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Hodoniczky J; Morris CA; Rae AL, 2012, 'Oral and intestinal digestion of oligosaccharides as potential sweeteners: A systematic evaluation', in Food Chemistry, pp. 1951 - 1958, http://dx.doi.org/10.1016/j.foodchem.2011.12.031
2012
Fung K; Morris C; Duncan M, 2002, 'Mass spectrometric techniques applied to the analysis of human tears: A focus on the peptide and protein constituents', in Advances in Experimental Medicine and Biology, pp. 601 - 605
2002
Hollis-Watt K; Morris C, 1999, 'Tear protein deposition on commercially available contact lenses', in Australian Society for Biomaterials Annual Meeting 1999, Australian Society for Biomaterials Annual Meeting 1999, Canberra, pp. 18 - 18, presented at Australian Society for Biomaterials Annual Meeting 1999, Canberra, 01 March 1999
1999
Hollis-Watt K; Morris C, 1999, 'Tear protein deposition on commercially available contact lenses', in 8th Scientific Meeting in Optometry, 8th Scientific Meeting in Optometry, Sydney, presented at 8th Scientific Meeting in Optometry, Sydney, 01 July 1999
1999
St John HAW; Kingshott P; Griesser HJ; Morris C; Bolis S, 1997, 'Surface characterization of worn hydrogel contact lenses', in Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, pp. 83 - 84
1997
Bolis S; Morris C; St John H; Griesser HJ; Sweeney DF; Holden BA, 1997, 'Tear component uptake during extended wear of a new oxygen permeable contact lens', in Investigative Ophthalmology and Visual Science, Association of Research Vision Ophthalmology Inc, Rockville, MD, USA, pp. 673, presented at ARVO 1997: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, 11 May 1997 - 16 May 1997
1997
Cole NA; Willcox MD; Tout S; Bao S; Stapleton FJ; Morris C; Husband A, 1997, 'Corneal infection with Pseudomonas aeruginosa causes ulceration and produces IL-6 infiltrating neutrophils', in Husband AJ; Beagley K; Clancy R; Collins A (eds.), 9th International Congress of Mucosal Immunology, 9th International Congress of Mucosal Immunology, Sydney, pp. 327 - 335, presented at 9th International Congress of Mucosal Immunology, Sydney, 01 January 1997
1997
Sack RA; Underwood A; Kah Ooi Tan ; Morris C, 1994, 'Vitronectin in human tears - Protection against closed eye induced inflammatory damage', in Advances in Experimental Medicine and Biology, pp. 345 - 349
1994
Journal articles
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Thawornchaisit P; Amornsak W; Mahannop P; Buddhirakkul P; Pandii W; Connellan P; Thompson D; Brushett D; Morris C, 2012, 'Combined Neem oil 6% w/w and Eucalyptus oil 16% w/w lotion for treating head lice: In vitro and in vivo efficacy studies', Journal of Pharmacy Practice and Research, vol. 42, pp. 189 - 192, http://dx.doi.org/10.1002/j.2055-2335.2012.tb00167.x
2012
Liu L; Winter KM; Stevenson L; Morris C; Leach DN, 2012, 'Wheat bran lipophilic compounds with in vitro anticancer effects', Food Chemistry, vol. 130, pp. 156 - 164, http://dx.doi.org/10.1016/j.foodchem.2011.07.023
2012
Myers SP; O'Connor J; Fitton JH; Brooks L; Rolfe M; Connellan P; Wohlmuth H; Cheras PA; Morris C, 2011, 'A combined Phase I and II open-label study on the Immunomodulatory effects of seaweed extract nutrient complex', Biologics: Targets and Therapy, vol. 5, pp. 45 - 60, http://dx.doi.org/10.2147/BTT.S12535
2011
Liu L; Deseo MA; Morris C; Winter KM; Leach DN, 2011, 'Investigation of α-glucosidase inhibitory activity of wheat bran and germ', Food Chemistry, vol. 126, pp. 553 - 561, http://dx.doi.org/10.1016/j.foodchem.2010.11.041
2011
Thakur M; Connellan P; Deseo MA; Morris C; Dixit VK, 2011, 'Immunomodulatory polysaccharide from chlorophytum borivilianum roots', Evidence-based Complementary and Alternative Medicine, vol. 2011, http://dx.doi.org/10.1093/ecam/neq012
2011
Thakur M; Thompson D; Connellan P; Deseo MA; Morris C; Dixit VK, 2011, 'Improvement of penile erection, sperm count and seminal fructose levels in vivo and nitric oxide release in vitro by ayurvedic herbs', Andrologia, vol. 43, pp. 273 - 277, http://dx.doi.org/10.1111/j.1439-0272.2010.01068.x
2011
Myers SP; O'Connor J; Fitton JH; Brooks L; Rolfe M; Connellan P; Wohlmuth H; Cheras PA; Morris C, 2010, 'A combined phase I and II open label study on the effects of a seaweed extract nutrient complex on osteoarthritis', Biologics: Targets and Therapy, vol. 4, pp. 33 - 44
2010
Myers SP; Stevenson L; Cheras PA; O'Connor J; Brooks L; Rolfe M; Conellan P; Morris C, 2010, 'A forced titration study of the antioxidant and immunomodulatory effects of Ambrotose AO supplement', BMC Complementary and Alternative Medicine, vol. 10, http://dx.doi.org/10.1186/1472-6882-10-16
2010
Mulder AM; Connellan PA; Oliver CJ; Morris CA; Stevenson LM, 2008, 'Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males', Nutrition Research, vol. 28, pp. 583 - 589, http://dx.doi.org/10.1016/j.nutres.2008.05.007
2008
Lane JD; Krumholz DM; Sack RA; Morris C, 2006, 'Tear glucose dynamics in diabetes mellitus', Current Eye Research, vol. 31, pp. 895 - 901, http://dx.doi.org/10.1080/02713680600976552
2006
Sack RA; Conradi L; Krumholz D; Beaton A; Sathe S; Morris C, 2005, 'Membrane array characterization of 80 chemokines, cytokines, and growth factors in open- and closed-eye tears: Angiogenin and other defense system constituents', Investigative Ophthalmology and Visual Science, vol. 46, pp. 1228 - 1238, http://dx.doi.org/10.1167/iovs.04-0760
2005
George M; Pierce G; Gabriel M; Morris C; Ahearn D, 2005, 'Effects of quorum sensing molecules of Pseudomonas aeruginosa on organism growth, elastase B production, and primary adhesion to hydrogel contact lenses', Eye and Contact Lens, vol. 31, pp. 54 - 61, http://dx.doi.org/10.1097/01.ICL.0000146324.28865.E8
2005
Fung KYC; Morris C; Sathe S; Sack R; Duncan MW, 2004, 'Characterization of the in vivo forms of lacrimal-specific proline-rich proteins in human tear fluid', Proteomics, vol. 4, pp. 3953 - 3959, http://dx.doi.org/10.1002/pmic.200300849
2004
Szliter EA; Morris CA; Carney F; Gabriel MM; Hazlett LD, 2002, 'Development of a new extended-wear contact lens model in the rat.', The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc, vol. 28, pp. 119 - 123
2002
Sack RA; Nunes I; Beaton A; Morris C, 2001, 'Host-defense mechanism of the ocular surfaces', Bioscience Reports, vol. 21, pp. 463 - 480, http://dx.doi.org/10.1023/A:1017943826684
2001
Mold C; Morris CA, 2001, 'Complement activation by apoptotic endothelial cells following hypoxia/reoxygenation', Immunology, vol. 102, pp. 359 - 364, http://dx.doi.org/10.1046/j.1365-2567.2001.01192.x
2001
Morris C; Franklin V; Tighe B; Graham M; Tan I, 2000, 'Biocompatibility of a high Dk fluorosilicone hydrogel during extended wear', Optometry and Vision Science, vol. 77, pp. 176
2000
Carrington SD; Hicks S; Corfield AP; Kaswan RL; Packer N; Bolis S; Morris C, 1998, 'Structural analysis of secreted ocular mucins in canine dry eye', Advances in Experimental Medicine and Biology, vol. 438, pp. 253 - 263
1998
Romero IR; Morris C; Rodriguez M; Du Clos TW; Mold C, 1998, 'Inflammatory potential of C-reactive protein complexes compared to immune complexes', Clinical Immunology and Immunopathology, vol. 87, pp. 155 - 162, http://dx.doi.org/10.1006/clin.1997.4516
1998
Hjelle B; Jenison S; Torrez-Martinez N; Herring B; Quan S; Polito A; Pichuantes S; Yamada T; Morris C; Elgh F; Lee HW; Artsob H; Dinello R, 1997, 'Rapid and specific detection of Sin Nombre virus antibodies in patients with hantavirus pulmonary syndrome by a strip immunoblot assay suitable for field diagnosis', Journal of Clinical Microbiology, vol. 35, pp. 600 - 608
1997
Morris C; Ball MS; Facker NH, 1997, 'Chemical characterisation of bovine conjunctival, mucin spfcies', Investigative Ophthalmology and Visual Science, vol. 38
1997
Bolis S; Ball M; Devine P; Morris C, 1996, 'Mucin species in the human tear film', Investigative Ophthalmology and Visual Science, vol. 37
1996
Sheehan M; Morris CA; Pussell BA; Charlesworth JA, 1995, 'Complement inhibition by human vitronectin involves non-heparin binding domains', Clinical and Experimental Immunology, vol. 101, pp. 136 - 141
1995
Yamada T; Hjelle B; Lanzi R; Morris C; Anderson B; Jenison S, 1995, 'Antibody responses to Four Corners hantavirus infections in the deer mouse (Peromyscus maniculatus): Identification of an immunodominant region of the viral nucleocapsid protein', Journal of Virology, vol. 69, pp. 1939 - 1943
1995
Morris CA; Underwood PA; Bean PA; Sheehan M; Charlesworth JA, 1994, 'Relative topography of biologically active domains of human vitronectin. Evidence from monoclonal antibody epitope and denaturation studies', Journal of Biological Chemistry, vol. 269, pp. 23845 - 23852
1994
Jenison S; Yamada T; Morris C; Anderson B; Torrez-Martinez N; Keller N; Hjelle B, 1994, 'Characterization of human antibody responses to four corners hantavirus infections among patients with hantavirus pulmonary syndrome', Journal of Virology, vol. 68, pp. 3000 - 3006
1994
Milis L; Morris CA; Sheehan MC; Charlesworth JA; Pussell BA, 1993, 'Vitronectin-mediated inhibition of complement: Evidence for different binding sites for C5b-7 and C9', Clinical and Experimental Immunology, vol. 92, pp. 114 - 119
1993
Sack RA; Underwood PA; Tan KO; Sutherland H; Morris CA, 1993, 'Vitronectin: Possible contribution to the closed-Eye external host-defense mechanism', Ocular Immunology and Inflammation, vol. 1, pp. 327 - 336, http://dx.doi.org/10.3109/09273949309057060
1993
Milis L; Timmermans V; Morris CA; Pussell BA; Charlesworth JA, 1992, 'The value of complement measurements in the assessment of lupus activity', Australian and New Zealand Journal of Medicine, vol. 22, pp. 338 - 344, http://dx.doi.org/10.1111/j.1445-5994.1992.tb02144.x
1992
Brown GM; Morris CA; Mitnick MA; Insogna KL, 1990, 'Treatment of humoral hypercalcemia of malignancy in rats with inhibitors of carbonic anhydrase', Journal of Bone and Mineral Research, vol. 5, pp. 1037 - 1041, http://dx.doi.org/10.1002/jbmr.5650051007
1990
Morris CA; Mitnick ME; Weir EC; Horowitz M; Kreider BL; Insogna KL, 1990, 'The parathyroid hormone-related protein stimulates human osteoblast-like cells to secrete a 9, 000 dalton bone-resorbing protein', Endocrinology, vol. 126, pp. 1783 - 1785, http://dx.doi.org/10.1210/endo-126-3-1783
1990
Insogna KL; Stewart AF; Morris CA; Hough LM; Milstone LM; Centrella M, 1989, 'Native and a synthetic analogue of the malignancy-associated parathyroid hormone-like protein have in vitro transforming growth factor-like properties', Journal of Clinical Investigation, vol. 83, pp. 1057 - 1060, http://dx.doi.org/10.1172/JCI113947
1989
Thorikay M; Kramer S; Reynolds FH; Sorvillo JM; Doescher L; Wu T; Morris CA; Burtis WJ; Insogna KL; Valenzuela DM; Stewart AF, 1989, 'Synthesis of a gene encoding parathyroid hormone-like protein-(1†141): Purification and biological characterization of the expressed protein', Endocrinology, vol. 124, pp. 111 - 118, http://dx.doi.org/10.1210/endo-124-1-111
1989
Weir EC; Burtis WJ; Morris CA; Brady TG; Insogna KL, 1988, 'Isolation of 16,000-dalton parathyroid hormone-like proteins from two animal tumors causing humoral hypercalcemia of malignancy', Endocrinology, vol. 123, pp. 2744 - 2751, http://dx.doi.org/10.1210/endo-123-6-2744
1988