Carol Morris

Adjunct Associate Professor

Carol obtained her PhD in Biochemistry from the University of Sydney in 1971, and after a 5 year Post-Doctoral period in Microbiology she built a research and teaching career in the Medical Sciences.  She has always been interested in the applied aspects of her scientific research, interspersing periods in Academia with some in Industry, including a small Australian start-up company in Diagnostics.  In 1992, through a chance meeting with Brien Holden, she began to focus her attention on the biology of the anterior eye, and contact lenses.  Carol has worked in R & D for two contact lens companies in the US, Cibavision (6 years) and more recently CooperVision (7 years), where she has contributed to areas of contact lens comfort, biocompatibility of materials and additives and the minimization of adverse events.   She is best known for her scientific contributions on the composition of tears; in health, in various physiological states and in disease.  During her career Carol has published over 40 research papers, two book chapters, successfully supervised 18 post-graduate students, given a number of invited presentations at Research Symposia, and is a named inventor on several issued patents and patent applications.  She is currently on the Editorial Board of Nutrition Research, and a frequent reviewer for IOVS, Eye and Contact Lens and Optometry and Vision Science.

publications

Conference Papers
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Hodoniczky J; Morris CA; Rae AL, 2012, 'Oral and intestinal digestion of oligosaccharides as potential sweeteners: A systematic evaluation', in Food Chemistry, pp. 1951 - 1958, http://dx.doi.org/10.1016/j.foodchem.2011.12.031
2012
Morris C; Willcox MD; Winterton LW; Lally J, 2006, 'A novel biomimetic surface on a contact lens?', in Contact Lens and Anterior Eye, Stockton Press, Basingstoke, UK, pp. 188 - 188, presented at British Contact Lens Association Annual Clinical Conference (BCLA 2006), Birmingham, England
2006
Fung K; Morris C; Duncan M, 2002, 'Mass spectrometric techniques applied to the analysis of human tears: A focus on the peptide and protein constituents', in Advances in Experimental Medicine and Biology, pp. 601 - 605, http://dx.doi.org/10.1007/978-1-4615-0717-8_84
2002
Keay LJ; Sweeney DF; Harmis N; Corrigan KM; Morris C; Willcox MD, 1999, 'Bacterial populations on high Dk lenses worn on a 30N EW schedule and on low Dk lenses worn on a 6N EW schedule', in 8th Scientific Meeting in Optometry, 8th Scientific Meeting in Optometry, Sydney, presented at 8th Scientific Meeting in Optometry, Sydney
1999
Hollis-Watt K; Morris C, 1999, 'Tear protein deposition on commercially available contact lenses', in Australian Society for Biomaterials Annual Meeting 1999, Australian Society for Biomaterials Annual Meeting 1999, Canberra, pp. 18 - 18, presented at Australian Society for Biomaterials Annual Meeting 1999, Canberra, 01 March 1999
1999
Hollis-Watt K; Morris C, 1999, 'Tear protein deposition on commercially available contact lenses', in 8th Scientific Meeting in Optometry, 8th Scientific Meeting in Optometry, Sydney, presented at 8th Scientific Meeting in Optometry, Sydney, 01 July 1999
1999
Cole NA; Willcox MD; Tout S; Bao S; Stapleton FJ; Morris C; Husband A, 1997, 'Corneal infection with Pseudomonas aeruginosa causes ulceration and produces IL-6 infiltrating neutrophils', in Husband AJ; Beagley K; Clancy R; Collins A (eds.), 9th International Congress of Mucosal Immunology, 9th International Congress of Mucosal Immunology, Sydney, pp. 327 - 335, presented at 9th International Congress of Mucosal Immunology, Sydney
1997
Tipireddy S; Willcox MD; Sack RA; Shivaji S; Morris C, 1997, 'Homestatic mechanisms that operate in the tear film during eye closure: Identification of tear borne complement regulators', in Husband AJ; Beagley K; Clancy R; Collins A (eds.), 9th International Congress of Mucosal Immunology, 9th International Congress of Mucosal Immunology, Sydney, pp. 337 - 346, presented at 9th International Congress of Mucosal Immunology, Sydney
1997
Tan ME; Morris C; Papas EB; Belmonte C; Holden BA, 1997, 'Conjunctival and corneal sensitivity in asymptomatic and symptomatic contact lens wearers', in Investigative Ophthalmology and Visual Science, Association of Research Vision Ophthalmology Inc, Rockville, MD, USA, pp. 1336, presented at ARVO 1997: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, 11 May 1997 - 16 May 1997
1997
Thakur A; Willcox MD; Morris C, 1997, 'Inflammatory mediators in contact lens induced red eye', in Husband AJ; Beagley K; Clancy R; Collins A (eds.), 9th International Congress of Mucosal Immunology, 9th International Congress of Mucosal Immunology, Sydney, pp. 347 - 353, presented at 9th International Congress of Mucosal Immunology, Sydney
1997
Morris C; Bolis S; Willcox MD; Walsh BR; Van Dyk DD; Ou K, 1997, 'Identification of human tear protein constituents by high resolution two dimensional gel electrophoresis', in Investigative Ophthalmology and Visual Science, Association of Research Vision Ophthalmology Inc, Rockville, MD, USA, pp. 768, presented at ARVO 1997: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, 11 May 1997 - 16 May 1997
1997
Holden BA; Reddy M; Sankaridurg P; Rajeev B; Sharma S; Willcox MD; Morris C; Sweeney DF; Rao GN, 1997, 'The histopathology of contact lens induced peripheral corneal ulcer', in Investigative Ophthalmology and Visual Science, Association of Research Vision Ophthalmology Inc, Rockville, MD, USA, pp. 981, presented at ARVO 1997: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, 11 May 1997 - 16 May 1997
1997
Carney FP; Morris C; Willcox MD; Milthorpe BK, 1997, 'The competitive binding of tear proteins to hydrogel lens polymers', in Investigative Ophthalmology and Visual Science, Association of Research Vision Ophthalmology Inc, Rockville, MD, USA, pp. 982, presented at ARVO 1997: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, 11 May 1997 - 16 May 1997
1997
Willcox MD; Cole NA; Stapleton FJ; Morris C; Husband A, 1997, 'In situ hybridisation demonstrates that the corneal epithelium produces inflammatory cytokines in response to Psuedomonas aeruginosa infection', in Investigative Ophthalmology and Visual Science, Association of Research Vision Ophthalmology Inc, Rockville, MD, USA, pp. 5332, presented at ARVO 1997: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, 11 May 1997 - 16 May 1997, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997WN21502153&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
1997
St John HAW; Kingshott P; Griesser HJ; Morris C; Bolis S, 1997, 'Surface characterization of worn hydrogel contact lenses', in Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, pp. 83 - 84
1997
Bolis S; Morris C; St John H; Griesser HJ; Sweeney DF; Holden BA, 1997, 'Tear component uptake during extended wear of a new oxygen permeable contact lens', in Investigative Ophthalmology and Visual Science, Association of Research Vision Ophthalmology Inc, Rockville, MD, USA, pp. 673, presented at ARVO 1997: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, 11 May 1997 - 16 May 1997
1997
Sack RA; Underwood A; Kah Ooi Tan ; Morris C, 1994, 'Vitronectin in human tears - Protection against closed eye induced inflammatory damage', in Advances in Experimental Medicine and Biology, pp. 345 - 349, http://dx.doi.org/10.1007/978-1-4615-2417-5_59
1994
Journal articles
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Thawornchaisit P; Amornsak W; Mahannop P; Buddhirakkul P; Pandii W; Connellan P; Thompson D; Brushett D; Morris C, 2012, 'Combined Neem oil 6% w/w and Eucalyptus oil 16% w/w lotion for treating head lice: In vitro and in vivo efficacy studies', Journal of Pharmacy Practice and Research, vol. 42, pp. 189 - 192, http://dx.doi.org/10.1002/j.2055-2335.2012.tb00167.x
2012
Liu L; Winter KM; Stevenson L; Morris C; Leach DN, 2012, 'Wheat bran lipophilic compounds with in vitro anticancer effects', Food Chemistry, vol. 130, pp. 156 - 164, http://dx.doi.org/10.1016/j.foodchem.2011.07.023
2012
Myers SP; O'Connor J; Fitton JH; Brooks L; Rolfe M; Connellan P; Wohlmuth H; Cheras PA; Morris C, 2011, 'A combined Phase I and II open-label study on the Immunomodulatory effects of seaweed extract nutrient complex', Biologics: Targets and Therapy, vol. 5, pp. 45 - 60, http://dx.doi.org/10.2147/BTT.S12535
2011
Liu L; Deseo MA; Morris C; Winter KM; Leach DN, 2011, 'Investigation of α-glucosidase inhibitory activity of wheat bran and germ', Food Chemistry, vol. 126, pp. 553 - 561, http://dx.doi.org/10.1016/j.foodchem.2010.11.041
2011
Thakur M; Connellan P; Deseo MA; Morris C; Dixit VK, 2011, 'Immunomodulatory polysaccharide from chlorophytum borivilianum roots', Evidence-based Complementary and Alternative Medicine, vol. 2011, http://dx.doi.org/10.1093/ecam/neq012
2011
Thakur M; Thompson D; Connellan P; Deseo MA; Morris C; Dixit VK, 2011, 'Improvement of penile erection, sperm count and seminal fructose levels in vivo and nitric oxide release in vitro by ayurvedic herbs', Andrologia, vol. 43, pp. 273 - 277, http://dx.doi.org/10.1111/j.1439-0272.2010.01068.x
2011
Myers SP; O'Connor J; Fitton JH; Brooks L; Rolfe M; Connellan P; Wohlmuth H; Cheras PA; Morris C, 2010, 'A combined phase I and II open label study on the effects of a seaweed extract nutrient complex on osteoarthritis', Biologics: Targets and Therapy, vol. 4, pp. 33 - 44, http://dx.doi.org/10.2147/btt.s8354
2010
Myers SP; Stevenson L; Cheras PA; O'Connor J; Brooks L; Rolfe M; Conellan P; Morris C, 2010, 'A forced titration study of the antioxidant and immunomodulatory effects of Ambrotose AO supplement', BMC Complementary and Alternative Medicine, vol. 10, http://dx.doi.org/10.1186/1472-6882-10-16
2010
Carney FP; Morris C; Milthorpe BK; Flanagan JL; Willcox MD, 2009, 'In vitro adsorption of tear proteins to hydroxyethyl methacrylate-based contact lens materials', Eye and Contact Lens, vol. 35, pp. 320 - 328, http://dx.doi.org/10.1097/ICL.0b013e3181becd3c
2009
Mulder AM; Connellan PA; Oliver CJ; Morris CA; Stevenson LM, 2008, 'Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males', Nutrition Research, vol. 28, pp. 583 - 589, http://dx.doi.org/10.1016/j.nutres.2008.05.007
2008
Lane JD; Krumholz DM; Sack RA; Morris C, 2006, 'Tear glucose dynamics in diabetes mellitus', Current Eye Research, vol. 31, pp. 895 - 901, http://dx.doi.org/10.1080/02713680600976552
2006
George M; Pierce G; Gabriel M; Morris C; Ahearn D, 2005, 'Effects of quorum sensing molecules of Pseudomonas aeruginosa on organism growth, elastase B production, and primary adhesion to hydrogel contact lenses', Eye and Contact Lens, vol. 31, pp. 54 - 61, http://dx.doi.org/10.1097/01.ICL.0000146324.28865.E8
2005
Sack RA; Conradi L; Krumholz D; Beaton A; Sathe S; Morris C, 2005, 'Membrane array characterization of 80 chemokines, cytokines, and growth factors in open- and closed-eye tears: Angiogenin and other defense system constituents', Investigative Ophthalmology and Visual Science, vol. 46, pp. 1228 - 1238, http://dx.doi.org/10.1167/iovs.04-0760
2005
Fung KYC; Morris C; Sathe S; Sack R; Duncan MW, 2004, 'Characterization of the in vivo forms of lacrimal-specific proline-rich proteins in human tear fluid', Proteomics, vol. 4, pp. 3953 - 3959, http://dx.doi.org/10.1002/pmic.200300849
2004
Szliter EA; Morris CA; Carney F; Gabriel MM; Hazlett LD, 2002, 'Development of a new extended-wear contact lens model in the rat.', The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc, vol. 28, pp. 119 - 123
2002
Sack RA; Nunes I; Beaton A; Morris C, 2001, 'Host-defense mechanism of the ocular surfaces', Bioscience Reports, vol. 21, pp. 463 - 480, http://dx.doi.org/10.1023/A:1017943826684
2001
Mold C; Morris CA, 2001, 'Complement activation by apoptotic endothelial cells following hypoxia/reoxygenation', Immunology, vol. 102, pp. 359 - 364, http://dx.doi.org/10.1046/j.1365-2567.2001.01192.x
2001
Keay LJ; Willcox MD; Sweeney DF; Morris C; Harmis N; Corrigan KM; Holden BA, 2001, 'Bacterial populations on 30-night extended wear silicone hydrogel lenses', CLAO Journal, vol. 27, pp. 30 - 34
2001
Morris C; Franklin V; Tighe B; Graham M; Tan I, 2000, 'Biocompatibility of a high Dk fluorosilicone hydrogel during extended wear', Optometry and Vision Science, vol. 77, pp. 176, http://dx.doi.org/10.1097/00006324-200012001-00290
2000
Sack RA; Beaton AR; Sathe S; Morris C; Willcox MD; Bogart B, 2000, 'Towards a closed eye model of the pre-ocular tear layer', Progress in Retinal and Eye Research, vol. 19, pp. 649 - 668, http://dx.doi.org/10.1016/S1350-9462(00)00006-9
2000
Stapleton FJ; Willcox MD; Morris C; Sweeney DF, 1998, 'Tear changes in contact lens wearers following overnight eye closure', Current Eye Research, vol. 17, pp. 183 - 188, http://dx.doi.org/10.1076/ceyr.17.2.183.5597
1998
Romero IR; Morris C; Rodriguez M; Du Clos TW; Mold C, 1998, 'Inflammatory potential of C-reactive protein complexes compared to immune complexes', Clinical Immunology and Immunopathology, vol. 87, pp. 155 - 162, http://dx.doi.org/10.1006/clin.1997.4516
1998
Glasson MJ; Molloy M; Walsh BR; Willcox MD; Morris C; Williams KK, 1998, 'Development of mini-gel technology in two-dimensional electrophoresis for mass-screening of samples: Application to tears', Electrophoresis, vol. 19, pp. 852 - 855, http://dx.doi.org/10.1002/elps.1150190541
1998
Carney FP; Keay LJ; Stapleton FJ; Morris C; Willcox MD, 1998, 'Hydrogel lens wettability and deposition in vivo', Clinical and Experimental Optometry, vol. 81, pp. 51 - 62, http://dx.doi.org/10.1111/j.1444-0938.1998.tb06626.x
1998
Carrington SD; Hicks S; Corfield AP; Kaswan RL; Packer N; Bolis S; Morris C, 1998, 'Structural analysis of secreted ocular mucins in canine dry eye', Advances in Experimental Medicine and Biology, vol. 438, pp. 253 - 263
1998
Morris C; Holden BA; Papas EB; Griesser HJ; Bolis S; Anderton PJ; Carney FP, 1998, 'The ocular surface, the tear film and the wettability of contact lenses', Advances in Experimental Medicine and Biology, vol. 438, pp. 717 - 722
1998
Carney FP; Morris C; Willcox MD, 1997, 'The effect of hydrogel lens wear on the major tear proteins during extended wear', Australian and New Zealand Journal of Ophthalmology, vol. 25, pp. S36 - S38
1997
Hjelle B; Jenison S; Torrez-Martinez N; Herring B; Quan S; Polito A; Pichuantes S; Yamada T; Morris C; Elgh F; Lee HW; Artsob H; Dinello R, 1997, 'Rapid and specific detection of Sin Nombre virus antibodies in patients with hantavirus pulmonary syndrome by a strip immunoblot assay suitable for field diagnosis', Journal of Clinical Microbiology, vol. 35, pp. 600 - 608, http://dx.doi.org/10.1128/jcm.35.3.600-608.1997
1997
Molloy M; Bolis S; Herbert B; Ou K; Tyler MI; Van Dyk DD; Willcox MD; Gooley AA; Williams KK; Morris C; Walsh BR, 1997, 'Establishment of the human reflex tear 2D-PAGE reference map: a first step towards the diagnosis of disease', Electrophoresis, vol. 18, pp. 1 - 5
1997
Morris C; Ball MS; Facker NH, 1997, 'Chemical characterisation of bovine conjunctival, mucin spfcies', Investigative Ophthalmology and Visual Science, vol. 38
1997
Molloy MP; Bolis S; Herbert BR; Ou K; Tyler MI; Van Dyk DD; Willcox MDP; Gooley AA; Williams KL; Morris CA; Walsh BJ, 1997, 'Establishment of the human reflex tear two-dimensional polyacrylamide gel electrophoresis reference map: New proteins of potential diagnostic value', Electrophoresis, vol. 18, pp. 2811 - 2815, http://dx.doi.org/10.1002/elps.1150181516
1997
Tan ME; Thakur A; Morris C; Willcox MD, 1997, 'Presence of inflammatory mediators in tears of contact lens wearers and non-contact lens wearers', Australian and New Zealand Journal of Ophthalmology, vol. 25, pp. S27 - S29
1997
Willcox MD; Morris C; Thakur A; Sack RA; Wickson JE; Boey W, 1997, 'Complement and complement regulatory proteins in human tears.', Investigative Ophthalmology and Visual Science, vol. 38, pp. 1 - 8
1997
Sack RA; Sathe S; Hackworth LA; Willcox MDP; Holden BA; Morris CA, 1996, 'The effect of eye closure on protein and complement deposition on Group IV hydrogel contact lenses: Relationship to tear flow dynamics', Current Eye Research, vol. 15, pp. 1092 - 1100, http://dx.doi.org/10.3109/02713689608995140
1996
Thakur A; Willcox MDP; Morris CA; Holden BA, 1996, 'Inflammatory components of human tear fluid', Australian and New Zealand Journal of Ophthalmology, vol. 24, pp. 13 - 16, http://dx.doi.org/10.1111/j.1442-9071.1996.tb00983.x
1996
Sakata M; Bolis S; Papas E; Morphett J; Morris CA, 1996, 'Characterisation of mucins in the tear film of ocular prosthesis wearers', Australian and New Zealand Journal of Ophthalmology, vol. 24, pp. 2 - 5, http://dx.doi.org/10.1111/j.1442-9071.1996.tb00980.x
1996
Bolis S; Ball M; Devine P; Morris C, 1996, 'Mucin species in the human tear film', Investigative Ophthalmology and Visual Science, vol. 37
1996
Thakur A; Willcox MDP; Morris C; Holden BA, 1996, 'Inflammatory mediators of tear fluid and their role in corneal inflammation', Investigative Ophthalmology and Visual Science, vol. 37
1996
Morris C; Bolis S; Sakata M; Papas E, 1996, 'Mucin and protein species in the tear film of ocular prosthesis wearers', Investigative Ophthalmology and Visual Science, vol. 37
1996
Sathe S; Sack RA; Hackworth L; Morris C; Willcox M; Holden B, 1996, 'Approximation of tear flux during open and closed eye contact lens wear', Investigative Ophthalmology and Visual Science, vol. 37
1996
Yamada T; Hjelle B; Lanzi R; Morris C; Anderson B; Jenison S, 1995, 'Antibody responses to Four Corners hantavirus infections in the deer mouse (Peromyscus maniculatus): Identification of an immunodominant region of the viral nucleocapsid protein', Journal of Virology, vol. 69, pp. 1939 - 1943, http://dx.doi.org/10.1128/jvi.69.3.1939-1943.1995
1995
Sheehan M; Morris CA; Pussell BA; Charlesworth JA, 1995, 'Complement inhibition by human vitronectin involves non-heparin binding domains', Clinical and Experimental Immunology, vol. 101, pp. 136 - 141, http://dx.doi.org/10.1111/j.1365-2249.1995.tb02289.x
1995
Jenison S; Yamada T; Morris C; Anderson B; Torrez-Martinez N; Keller N; Hjelle B, 1994, 'Characterization of human antibody responses to four corners hantavirus infections among patients with hantavirus pulmonary syndrome', Journal of Virology, vol. 68, pp. 3000 - 3006, http://dx.doi.org/10.1128/jvi.68.5.3000-3006.1994
1994
Morris CA; Underwood PA; Bean PA; Sheehan M; Charlesworth JA, 1994, 'Relative topography of biologically active domains of human vitronectin. Evidence from monoclonal antibody epitope and denaturation studies', Journal of Biological Chemistry, vol. 269, pp. 23845 - 23852
1994
Milis L; Morris CA; Sheehan MC; Charlesworth JA; Pussell BA, 1993, 'Vitronectin-mediated inhibition of complement: Evidence for different binding sites for C5b-7 and C9', Clinical and Experimental Immunology, vol. 92, pp. 114 - 119, http://dx.doi.org/10.1111/j.1365-2249.1993.tb05956.x
1993
Sack RA; Underwood PA; Tan KO; Sutherland H; Morris CA, 1993, 'Vitronectin: Possible contribution to the closed-Eye external host-defense mechanism', Ocular Immunology and Inflammation, vol. 1, pp. 327 - 336, http://dx.doi.org/10.3109/09273949309057060
1993
Milis L; Timmermans V; Morris CA; Pussell BA; Charlesworth JA, 1992, 'The value of complement measurements in the assessment of lupus activity', Australian and New Zealand Journal of Medicine, vol. 22, pp. 338 - 344, http://dx.doi.org/10.1111/j.1445-5994.1992.tb02144.x
1992
Brown GM; Morris CA; Mitnick MA; Insogna KL, 1990, 'Treatment of humoral hypercalcemia of malignancy in rats with inhibitors of carbonic anhydrase', Journal of Bone and Mineral Research, vol. 5, pp. 1037 - 1041, http://dx.doi.org/10.1002/jbmr.5650051007
1990
Morris CA; Mitnick ME; Weir EC; Horowitz M; Kreider BL; Insogna KL, 1990, 'The parathyroid hormone-related protein stimulates human osteoblast-like cells to secrete a 9, 000 dalton bone-resorbing protein', Endocrinology, vol. 126, pp. 1783 - 1785, http://dx.doi.org/10.1210/endo-126-3-1783
1990
Thorikay M; Kramer S; Reynolds FH; Sorvillo JM; Doescher L; Wu T; Morris CA; Burtis WJ; Insogna KL; Valenzuela DM; Stewart AF, 1989, 'Synthesis of a gene encoding parathyroid hormone-like protein-(1†141): Purification and biological characterization of the expressed protein', Endocrinology, vol. 124, pp. 111 - 118, http://dx.doi.org/10.1210/endo-124-1-111
1989
Insogna KL; Stewart AF; Morris CA; Hough LM; Milstone LM; Centrella M, 1989, 'Native and a synthetic analogue of the malignancy-associated parathyroid hormone-like protein have in vitro transforming growth factor-like properties', Journal of Clinical Investigation, vol. 83, pp. 1057 - 1060, http://dx.doi.org/10.1172/JCI113947
1989
Weir EC; Burtis WJ; Morris CA; Brady TG; Insogna KL, 1988, 'Isolation of 16,000-dalton parathyroid hormone-like proteins from two animal tumors causing humoral hypercalcemia of malignancy', Endocrinology, vol. 123, pp. 2744 - 2751, http://dx.doi.org/10.1210/endo-123-6-2744
1988