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In this presentation, the roles that microglia play in regulating the normal mammalian retina will be summarized.
Microglia are resident immune cells in the retina and Central Nervous System, that are well known for their role in pathological conditions of the nervous system. Over recent years, it has emerged that microglia also play important roles in maintaining normal neuronal function-they constantly survey the synaptic regions of the nervous system. In this presentation, the roles that microglia play in regulating the normal mammalian retina will be summarized. In particular, our results show that microglia contact photoreceptor terminals and are important in regulating photoreceptor integrity.
Erica Fletcher is Professor in the Department of Anatomy and Neuroscience, at The University of Melbourne where she heads the Visual Neuroscience Laboratory. She is a clinically trained optometrist who holds both MSc and PhD degrees. She completed her PhD at The University of Melbourne and undertook postdoctoral training at the Max Planck Institute for Brain Research in Germany, funded by a CJ Martin Award from the NH&MRC. Prof Fletcher was appointed to an academic position in 2000 at The University of Melbourne. Since 2000, Prof Fletcher has had been funded continuously by the NH&MRC. In 2006 she was awarded the Irvin M and Beatrice Borish Award from the American Academy of Optometry for her contribution to vision research. Prof Fletcher’s research interests remain primarily focussed on understanding the causes of retinal degenerations.