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Streptococcus pneumoniae (the pneumococcus) is the world’s foremost bacterial pathogen, killing more than 1 million individuals every year. Essential to its ability to cause disease is the acquisition of essential metal ions from the host environment. This seminar will discuss the biochemical and biophysical determinants that enable this pathogen to selectively acquire specific metal ions from the host environment and will also reveal how it subverts host resistance mechanisms to this process.
Christopher McDevitt obtained a PhD in Microbiology and Biochemistry from the University of Queensland, Australia. He then undertook two postdoctoral roles studying membrane transport proteins, in the laboratories of Prof. Ben Berks and A/Prof. Richard Callaghan, at the University of Oxford, UK. In 2008, he relocated to the University of Adelaide, to take up a position in the Research Centre for Infectious Disease (RCID). In 2012, he established his own laboratory at Adelaide focussing on the chemical biology of bacterial pathogens. Currently, he is an ARC Future Fellow and serves as the Deputy Director of the RCID.